Nucleic Acid Synthesis
Medchemexpress LLC Nucleoside-Analog-2 | 876708-01-9 | ≥95.0% | C9H11N5O6 | 50 MG
Nucleoside-Analog-2 is a 4'-Azidocytidine analogue that targets Hepatitis C virus (HCV) replication. It functions as a click chemistry reagent due to its Azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups.
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Targets Hepatitis C virus (HCV) replication.
Abcam BrdU (5-bromo-2'-deo x yuridine), Thymidine analog, 500MG
BrdU (5-bromo-2'-deoxyuridine), a thymidine analog, naturally incorporates into proliferating cells. Labels DNA, a useful marker for the study of DNA synthesis. Decreases TTP pools in vitro. Antitumor and radiation-sensitizing agent. Active in vitro and in vivo. - Cited in over 75 publications - Purity > 98% - Solubility: Dimethylacetamide ~ 200 (mg/mL), soluble in water to 50 mM
The product is subject to the following: Abcam Restricted Use Statement
![Revvity Health Sciences Inc Guanosine 5'-triphosphate, [8-<sup>3</sup>H], (GTP,[<sup>3</sup>H])](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502105566.jpg-250.jpg)
Revvity Health Sciences Inc Guanosine 5'-triphosphate, [8-3H], (GTP,[3H])
Guanosine 5'-triphosphate, [8-3H], (GTP,[3H])
Medchemexpress LLC 5-Methylcytidine 5′-triphosphate trisodium | 327174-86-7 | >99.6% | 563.13 | 57 MG
5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. It can be used in replacing unmodified mRNA, which leads to an increase in translational properties and stability, and a reduction in innate immune responses in human and other mammalian cells.
- Modified nucleoside triphosphate
- Increases translational properties and stability
- Reduces innate immune responses in human and mammalian cells
Abcam Ribavirin, Antiviral nucleoside, 10MG
MW 244.21 g/mol, Purity >99%. A non interferon-inducing, broad spectrum antiviral nucleoside. Active metabolites interfere with viral replication. Shows antiviral activity against a number of viruses including Hepatitis C, influenza and polio.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BrdU (5-bromo-2'-deo x yuridine), Thymidine analog, 5G
BrdU (5-bromo-2'-deoxyuridine), a thymidine analog, naturally incorporates into proliferating cells. Labels DNA, a useful marker for the study of DNA synthesis. Decreases TTP pools in vitro. Antitumor and radiation-sensitizing agent. Active in vitro and in vivo. - Cited in over 75 publications - Purity > 98% - Solubility: Dimethylacetamide ~ 200 (mg/mL), soluble in water to 50 mM
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC 3'-O-methylcytidine | 20594-00-7 | 98.0% | 257.24 g/mol | C10H15N3O5 | 1 ML
3'-O-Methylcytidine is a cytidine nucleoside analog supplied for research use. It is offered both as a solid and as pre-made stock solutions for biochemical and nucleic acid studies, and is characterized by defined molecular properties and recommended storage conditions.
- Molecular formula C10H15N3O5 and molecular weight 257.24 g/mol.
- Purity: 98.0% as reported by the manufacturer.
- Soluble in DMSO at ≥100 mg/mL (≈388.7 mM), suitable for stock solution preparation.
- Available in small solid quantities and common stock concentrations for immediate use.
- Store solid protected from light at 4°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Intended for research use only; follow appropriate safety and handling procedures.
Medchemexpress LLC 2'-O-Methyluridine-d3 | 2140-76-3 | 99.2% | 261.25 | 1 MG
2'-O-Methyluridine-d3 is deuterium labeled 2'-O-Methyluridine (HY-W011824). 2'-O-Methyluridine is a modified nucleoside found in *T. thermophile* tRNA. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs. The level of 2'-O-Methyluridine in serum is decreased in patients with breast cancer. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Abcam Anti-BrdU antibody [MoBu-1]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2748032.png-250.jpg)
Abcam Anti-BrdU antibody [MoBu-1]
Mouse monoclonal [MoBu-1] to BrdU
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC 4-Thio-dTTP 10ul (100 mM)
4-Thio-dTTP is a nucleotide analog structurally similar to thymidine triphosphate (dTTP) It incorporates into DNA strands during enzymatic synthesis modifying nucleic acid interactions and affecting the activities of enzymes involved in DNA replication and repair 4-Thio-dTTP exerts its biological activity through incorporation into DNA enabling the study of DNA polymerase fidelity replication kinetics enzyme-substrate interactions and mechanisms of DNA damage responses Based on these biochemical properties 4-Thio-dTTP holds research potential in applications such as investigating DNA synthesis regulation enzymatic mechanisms and pathways related to cancer and genomic instability
Sigma Aldrich Fine Chemicals Biosciences Nucleoside 5-Diphosphate K
Nucleoside Diphosphate Kinase exists in two isoforms in eukaryotic cells NDK-A and NDK-B. These enzymes are found expressed both in the mitochondria and the cytoplasm.
![Abcam Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate, 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502583226.JPG-250.jpg)
Abcam Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate, 100MG
MW 487.17 g/mol, Purity >98%. Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Pseudouridine | 1445-07-4 | 99.9% | 244.20 | 10 MG
Pseudouridine is an isomer of uridine and the most abundant modified nucleoside found in non-coding RNA. It plays a crucial role in fine-tuning and stabilizing regional structures in rRNA and tRNA, which are essential for their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments show potential for inhibiting aberrant protein synthesis and are promising for research related to myelodysplastic syndrome (MDS)-related leukemia.
- Isomer of uridine and most abundant modified nucleoside in non-coding RNA.
- Fine-tunes and stabilizes regional structures in rRNA and tRNA.
- Essential for mRNA decoding, ribosome assembly, processing, and translation.
- Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis.
- Holds promise for research on myelodysplastic syndrome (MDS)-related leukemia.
Medchemexpress LLC 3-Methylcytidine | 2140-64-9 | 99.3% | 257.24 | 100 MG
3-Methylcytidine is a urinary nucleoside that can serve as a biomarker for four types of cancer, including lung cancer, gastric cancer, colon cancer, and breast cancer. Studies have shown it to be significantly upregulated in the urine samples of breast cancer patients, indicating its potential utility in diagnostic applications.
- Biomarker for lung, gastric, colon, and breast cancers
- Upregulated in urine samples of breast cancer patients
- Urinary nucleoside
Abcam Resorufin b-D-glucopyranoside, 10MG
MW 375.3 Da, Purity >95%. Stable β-glucosidase probe (470nm). Releases the red fluorescent dye resorufin M0202 upon β-glucosidase enzyme cleavage. Successful in numerous applications in cell biology, high-throughput and high-content screening and diagnostics.
The product is subject to the following: Abcam Restricted Use Statement